platform
Biocomplex is specialized in macromolecular sample preparation and purification for functional and structural studies using preparative ultracentrifugation, monolithic chromatography and asymmetrical flow field-flow fractionation technologies. Biocomplex also actively develops new purification methods for large biopolymers, often in co-operation with manufacturers. Our technologies can be used in different combinations to purify large macromolecular complexes such as viruses, virus-like particles, viral subassemblies, exosomes, membrane vesicles, large protein complexes, and ribonucleoprotein complexes as an important first step in the structure analysis pipeline. Samples produced at Biocomplex can be further studied at the CryoEM facility located in the same building (see Electron Microscopy, Helsinki). We accept both visits and shipped samples. Please contact grp-biocomplexservice@helsinki.fi for enquiries.
If you aim to work with genetically modified organisms or your work requires Biosafety Level 2 (BSL2) facility, please contact us in advance (grp-biocomplexservice@helsinki.fi). Both genetically modified organisms and Biosafety Level 2 samples (Finnish criteria) can be handled but may require acquisition of permits.
Instruments available: Biocomplex instruments.