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We have applied some changes to ARIA and are monitoring stability, but you can continue to work as normal. We appreciate your understanding.

Native Mass Spectrometry, Oxford, UK

Native Mass Spectrometry is the utilisation of soft ionisation methods and biological like sample conditions to allow a mass spectrum of a natively folded (i.e. not denatured) protein to be collected. Coupled with high resolution and highly sensitive detectors, this allows for: accurate mass, stoichiometry and, in some cases, small molecule/lipid binding partner determination.

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Instruct Centre

University of Oxford

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User Guide

Native MS is highly-complementary to almost all the tools that are currently used in structural biology. From relatively small quantities of starting material, this technique can rapidly provide fundamental information to a structural biologist.